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Concurrent activation of β(2)-adrenergic receptor and blockage of GPR55 disrupts pro-oncogenic signaling in glioma cells
Activation of β(2)-adrenergic receptor (β(2)AR) and deorphanized GPR55 has been shown to modulate cancer growth in diverse tumor types in vitro and in xenograft models in vivo. (R,R′)-4′-methoxy-1-naphthylfenoterol [(R,R′)-MNF] is a bivalent compound that agonizes β(2)AR but inhibits GPR55-mediated...
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| Publicado no: | Cell Signal |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512002/ https://ncbi.nlm.nih.gov/pubmed/28495590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.05.006 |
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