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GPR55 receptor antagonist decreases glycolytic activity in PANC-1 pancreatic cancer cell line and tumor xenografts

The Warburg effect is a predominant metabolic pathway in cancer cells characterized by enhanced glucose uptake and its conversion to L-lactate and is associated with upregulated expression of HIF-1α and activation of the EGFR-MEK-ERK, Wnt-β-catenin and PI3K-AKT signaling pathways. (R,R’)-4’-methoxy-...

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Bibliografische gegevens
Gepubliceerd in:Int J Cancer
Hoofdauteurs: Bernier, Michel, Catazaro, Jonathan, Singh, Nagendra S., Wnorowski, Artur, Boguszewska-Czubara, Anna, Jozwiak, Krzysztof, Powers, Robert, Wainer, Irving W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028007/
https://ncbi.nlm.nih.gov/pubmed/28741686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30904
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