First Infusion Reactions are Mediated by FcγRIIIb and Neutrophils

PURPOSE: Administration of therapeutic monoclonal antibodies (mAbs) is frequently accompanied by severe first infusion reactions (FIR). The mechanism driving FIR is still unclear. This study aimed to investigate the cellular and molecular mechanisms causing FIR in humanized mouse models and their po...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharm Res
Egile Nagusiak: Weber, Felix, Breustedt, Daniel, Schlicht, Sonja, Meyer, Claas A., Niewoehner, Jens, Ebeling, Martin, Freskgard, Per-Ola, Bruenker, Peter, Singer, Thomas, Reth, Michael, Iglesias, Antonio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer US 2018
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021477/
https://ncbi.nlm.nih.gov/pubmed/29951887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2448-8
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