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ADAM17 cleaves CD16b (FcγRIIIb) in human neutrophils
CD16b (FcγRIIIb) is exclusively expressed by human neutrophils and binds IgG in immune complexes. Cell surface CD16b undergoes efficient ectodomain shedding upon neutrophil activation and apoptosis. Indeed, soluble CD16b is present at high levels in the plasma of healthy individuals, which appears t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556181/ https://ncbi.nlm.nih.gov/pubmed/23228566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.11.027 |
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