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Regulation of CXCR2 expression and function by a disintegrin and metalloprotease-17 (ADAM17)
The chemokine receptor CXCR2 is expressed at high levels on circulating neutrophils and is critical for directing their migration to sites of inflammation. CXCR2 surface levels are rapidly modulated by 2 mechanisms—cell internalization and recycling upon ligand binding—and by a metalloprotease activ...
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| Publicado no: | J Leukoc Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4338845/ https://ncbi.nlm.nih.gov/pubmed/25412626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI0714-340R |
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