NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)

The Fc receptor CD16 is present on essentially all CD56(dim) peripheral blood natural killer (NK) cells. Upon recognition of antibody-coated cells it delivers a potent signal to NK cells, which eliminate targets through direct killing and cytokine production. Here we investigated the regulation of C...

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Bibliographische Detailangaben
Hauptverfasser: Romee, Rizwan, Foley, Bree, Lenvik, Todd, Wang, Yue, Zhang, Bin, Ankarlo, Dave, Luo, Xianghua, Cooley, Sarah, Verneris, Mike, Walcheck, Bruce, Miller, Jeffrey
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2013
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643761/
https://ncbi.nlm.nih.gov/pubmed/23487023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-425397
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