Different proteolytic mechanisms involved in FcγRIIIb shedding from human neutrophils

The Fcγ receptor type IIIb (CD16) is highly expressed on human neutrophils and is found in a soluble form in plasma and in other body fluids. Upon activation of neutrophils in vitro, FcγRIIIb is shed from the cell surface by proteolytic cleavage. We have now investigated the effect of metalloprotein...

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Detalhes bibliográficos
Principais autores: Middelhoven, P J, Van Buul, J D, Hordijk, P L, Roos, D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Rheumatic Disease/Vasculitis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906091/
https://ncbi.nlm.nih.gov/pubmed/11472441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01548.x
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