Different proteolytic mechanisms involved in FcγRIIIb shedding from human neutrophils

The Fcγ receptor type IIIb (CD16) is highly expressed on human neutrophils and is found in a soluble form in plasma and in other body fluids. Upon activation of neutrophils in vitro, FcγRIIIb is shed from the cell surface by proteolytic cleavage. We have now investigated the effect of metalloprotein...

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Bibliografiske detaljer
Main Authors: Middelhoven, P J, Van Buul, J D, Hordijk, P L, Roos, D
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2001
Fag:
Rheumatic Disease/Vasculitis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906091/
https://ncbi.nlm.nih.gov/pubmed/11472441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01548.x
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