Neutrophil FcγRIIIb allelic polymorphism in anti-neutrophil cytoplasmic antibody (ANCA)-positive systemic vasculitis

Neutrophils constitutively express FcγRIIa and FcγRIIIb receptors. Both receptors exhibit allelic variants which have different quantitative functional capacities: the biallelic FcγRIIa-R131 and -H131 alleles, and the neutrophil antigen (NA) NA1/NA2 alleles. ANCA activation of neutrophils requires l...

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Bibliographic Details
Main Authors: Tse, W Y, Abadeh, S, Jefferis, R, Savage, C O S, Adu, D
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2000
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905578/
https://ncbi.nlm.nih.gov/pubmed/10691933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2000.01182.x
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