First Infusion Reactions are Mediated by FcγRIIIb and Neutrophils

PURPOSE: Administration of therapeutic monoclonal antibodies (mAbs) is frequently accompanied by severe first infusion reactions (FIR). The mechanism driving FIR is still unclear. This study aimed to investigate the cellular and molecular mechanisms causing FIR in humanized mouse models and their po...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Pharm Res
Autors principals: Weber, Felix, Breustedt, Daniel, Schlicht, Sonja, Meyer, Claas A., Niewoehner, Jens, Ebeling, Martin, Freskgard, Per-Ola, Bruenker, Peter, Singer, Thomas, Reth, Michael, Iglesias, Antonio
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021477/
https://ncbi.nlm.nih.gov/pubmed/29951887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-018-2448-8
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars