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Structure and assembly mechanisms of toxic human islet amyloid polypeptide oligomers associated with copper
Amyloidosis is a clinical disorder implicated with the formation of toxic amyloid aggregates. Despite their pathological significance, it is challenging to define the structural characteristics of amyloid oligomers owing to their metastable nature. Herein, we report structural and mechanistic invest...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6020819/ https://ncbi.nlm.nih.gov/pubmed/30155193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00153j |
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