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Islet amyloid polypeptide toxicity and membrane interactions
Islet amyloid polypeptide (IAPP) is responsible for amyloid formation in type 2 diabetes and contributes to the failure of islet cell transplants, however the mechanisms of IAPP-induced cytotoxicity are not known. Interactions with model anionic membranes are known to catalyze IAPP amyloid formation...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3845181/ https://ncbi.nlm.nih.gov/pubmed/24218607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305517110 |
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