Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology

The hormone islet amyloid polypeptide (IAPP, or amylin) plays a role in glucose homeostasis but aggregates to form islet amyloid in type-2 diabetes. Islet amyloid formation contributes to β-cell dysfunction and death in the disease and to the failure of islet transplants. Recent work suggests a role...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Akter, Rehana, Cao, Ping, Noor, Harris, Ridgway, Zachary, Tu, Ling-Hsien, Wang, Hui, Wong, Amy G., Zhang, Xiaoxue, Abedini, Andisheh, Schmidt, Ann Marie, Raleigh, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662979/
https://ncbi.nlm.nih.gov/pubmed/26649319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2798269
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