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Structure and assembly mechanisms of toxic human islet amyloid polypeptide oligomers associated with copper
Amyloidosis is a clinical disorder implicated with the formation of toxic amyloid aggregates. Despite their pathological significance, it is challenging to define the structural characteristics of amyloid oligomers owing to their metastable nature. Herein, we report structural and mechanistic invest...
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| 出版年: | Chem Sci |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Royal Society of Chemistry
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6020819/ https://ncbi.nlm.nih.gov/pubmed/30155193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00153j |
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