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The effect of curcumin on human islet amyloid polypeptide misfolding and toxicity

Type 2 diabetes involves aberrant misfolding of human islet amyloid polypeptide (h-IAPP) and resultant pancreatic amyloid deposits. Curcumin, a biphenolic small molecule, has offered potential benefits in other protein misfolding diseases, such as Alzheimer’s disease. Our aim was to investigate whet...

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Detalhes bibliográficos
Publicado no:Amyloid
Main Authors: DAVAL, MARIE, BEDROOD, SAHAR, GURLO, TATYANA, HUANG, CHANG-JIANG, COSTES, SAFIA, BUTLER, PETER C., LANGEN, RALF
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4394664/
https://ncbi.nlm.nih.gov/pubmed/21067307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13506129.2010.530008
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