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Topoisomerase II Poisons for Glioblastoma; Existing Challenges and Opportunities to Personalize Therapy

Despite advances in surgery, radiotherapy, and chemotherapy, glioblastoma (GBM) remains a malignancy with poor prognosis. The molecular profile of GBM is diverse across patients, and individual responses to therapy are highly variable. Yet, patients diagnosed with GBM are treated with a rather unifo...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Mehta, Amol, Awah, Chidiebere U., Sonabend, Adam M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019456/
https://ncbi.nlm.nih.gov/pubmed/29988316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00459
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