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Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB
Transient receptor potential (TRP) channels are involved in various physiological processes, including sensory transduction. The TRP channel TRPV6 mediates calcium uptake in epithelia and its expression is dramatically increased in numerous types of cancer. TRPV6 inhibitors suppress tumor growth, bu...
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6018633/ https://ncbi.nlm.nih.gov/pubmed/29941865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04828-y |
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