Opening of the Human Epithelial Calcium Channel TRPV6

Ca(2+)-selective transient receptor potential vanilloid subfamily member 6 (TRPV6) channels play a critical role in calcium uptake in epithelial tissues(1–4). Altered TRPV6 expression is associated with a variety of human diseases(5), including cancers(6). TRPV6 channels are constitutively active(1,...

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Pubblicato in:Nature
Autori principali: McGoldrick, Luke L., Singh, Appu K., Saotome, Kei, Yelshanskaya, Maria V., Twomey, Edward C., Grassucci, Robert A., Sobolevsky, Alexander I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854407/
https://ncbi.nlm.nih.gov/pubmed/29258289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25182
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