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Novel Inhibitor Discovery of Staphylococcus aureus Sortase B and the Mechanism Confirmation via Molecular Modeling

SortaseB (SrtB) plays a critical role in Staphylococcus aureus (S. aureus) infections. According to the reports in the literature, SrtB can anchor the IsdC to the cell wall to capture iron from the host to achieve a successful invasion. On the other hand, SrtB could also affect the adhesion of S. au...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Wang, Guizhen, Wang, Xiyan, Sun, Lin, Gao, Yawen, Niu, Xiaodi, Wang, Hongsu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017250/
https://ncbi.nlm.nih.gov/pubmed/29690584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040977
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