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Discovery of the Novel Inhibitor Against New Delhi Metallo-β-Lactamase Based on Virtual Screening and Molecular Modelling

New Delhi metallo-β-lactamase (NDM-1), one of the metallo-β-lactamases (MBLs), leads to antibiotic resistance in clinical treatments due to the strong ability of hydrolysis to almost all kinds of β-lactam antibiotics. Therefore, there is the urgent need for the research and development of the novel...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wang, Xiyan, Yang, Yanan, Gao, Yawen, Niu, Xiaodi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279046/
https://ncbi.nlm.nih.gov/pubmed/32443639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103567
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