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Virtual Screening and Experimental Testing of B1 Metallo-β-lactamase Inhibitors

The global rise of metallo-β-lactamases (MBLs) is problematic due to their ability to inactivate most β-lactam antibiotics. MBL inhibitors that could be co-administered with and restore the efficacy of β-lactams are highly sought after. In this study, we employ virtual screening of candidate MBL inh...

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Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Kang, Joon S., Zhang, Antonia L., Faheem, Mohammad, Zhang, Charles J., Ai, Ni, Buynak, John D., Welsh, William J., Oelschlaeger, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527342/
https://ncbi.nlm.nih.gov/pubmed/30107123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.8b00133
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