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Pterostilbene restores carbapenem susceptibility in New Delhi metallo‐β‐lactamase‐producing isolates by inhibiting the activity of New Delhi metallo‐β‐lactamases

BACKGROUND AND PURPOSE: Bacteria producing New Delhi metallo‐β‐lactamase‐1 (NDM‐1) are an increasing clinical threat. NDM‐1 can inactivate almost all β‐lactams and is not sensitive to any existing β‐lactamase inhibitors. To identify effective inhibitors of the NDM‐1 enzyme and clarify the mechanism...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Liu, Shui, Zhang, Jian, Zhou, Yonglin, Hu, Naiyu, Li, Jiyun, Wang, Yang, Niu, Xiaodi, Deng, Xuming, Wang, Jianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932935/
https://ncbi.nlm.nih.gov/pubmed/31376166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14818
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