Pterostilbene restores carbapenem susceptibility in New Delhi metallo‐β‐lactamase‐producing isolates by inhibiting the activity of New Delhi metallo‐β‐lactamases

BACKGROUND AND PURPOSE: Bacteria producing New Delhi metallo‐β‐lactamase‐1 (NDM‐1) are an increasing clinical threat. NDM‐1 can inactivate almost all β‐lactams and is not sensitive to any existing β‐lactamase inhibitors. To identify effective inhibitors of the NDM‐1 enzyme and clarify the mechanism...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: Liu, Shui, Zhang, Jian, Zhou, Yonglin, Hu, Naiyu, Li, Jiyun, Wang, Yang, Niu, Xiaodi, Deng, Xuming, Wang, Jianfeng
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932935/
https://ncbi.nlm.nih.gov/pubmed/31376166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14818
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