Pterostilbene restores carbapenem susceptibility in New Delhi metallo‐β‐lactamase‐producing isolates by inhibiting the activity of New Delhi metallo‐β‐lactamases

BACKGROUND AND PURPOSE: Bacteria producing New Delhi metallo‐β‐lactamase‐1 (NDM‐1) are an increasing clinical threat. NDM‐1 can inactivate almost all β‐lactams and is not sensitive to any existing β‐lactamase inhibitors. To identify effective inhibitors of the NDM‐1 enzyme and clarify the mechanism...

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Bibliografiska uppgifter
I publikationen:Br J Pharmacol
Huvudupphovsmän: Liu, Shui, Zhang, Jian, Zhou, Yonglin, Hu, Naiyu, Li, Jiyun, Wang, Yang, Niu, Xiaodi, Deng, Xuming, Wang, Jianfeng
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932935/
https://ncbi.nlm.nih.gov/pubmed/31376166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14818
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