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Investigation of the inhibition effect and mechanism of myricetin to Suilysin by molecular modeling

In the present study, the inhibitory effect and mechanism of myricetin, a natural flavonoid compound, in relation to Suilysin (SLY) were investigated through molecular dynamics simulations, mutational analysis and fluorescence-quenching assays. Myricetin is a potential inhibitor that does not exhibi...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Niu, Xiaodi, Sun, Lin, Wang, Guizhen, Gao, Yawen, Yang, Yanan, Wang, Xiyan, Wang, Hongsu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603505/
https://ncbi.nlm.nih.gov/pubmed/28924148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12168-y
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