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Novel Inhibitor Discovery of Staphylococcus aureus Sortase B and the Mechanism Confirmation via Molecular Modeling

SortaseB (SrtB) plays a critical role in Staphylococcus aureus (S. aureus) infections. According to the reports in the literature, SrtB can anchor the IsdC to the cell wall to capture iron from the host to achieve a successful invasion. On the other hand, SrtB could also affect the adhesion of S. au...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Wang, Guizhen, Wang, Xiyan, Sun, Lin, Gao, Yawen, Niu, Xiaodi, Wang, Hongsu
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017250/
https://ncbi.nlm.nih.gov/pubmed/29690584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040977
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