Novel Inhibitor Discovery of Staphylococcus aureus Sortase B and the Mechanism Confirmation via Molecular Modeling

SortaseB (SrtB) plays a critical role in Staphylococcus aureus (S. aureus) infections. According to the reports in the literature, SrtB can anchor the IsdC to the cell wall to capture iron from the host to achieve a successful invasion. On the other hand, SrtB could also affect the adhesion of S. au...

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Bibliographic Details
Published in:Molecules
Main Authors: Wang, Guizhen, Wang, Xiyan, Sun, Lin, Gao, Yawen, Niu, Xiaodi, Wang, Hongsu
Format: Artigo
Language:Inglês
Published: MDPI 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017250/
https://ncbi.nlm.nih.gov/pubmed/29690584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040977
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