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Novel Inhibitor Discovery of Staphylococcus aureus Sortase B and the Mechanism Confirmation via Molecular Modeling

SortaseB (SrtB) plays a critical role in Staphylococcus aureus (S. aureus) infections. According to the reports in the literature, SrtB can anchor the IsdC to the cell wall to capture iron from the host to achieve a successful invasion. On the other hand, SrtB could also affect the adhesion of S. au...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Molecules
मुख्य लेखकों: Wang, Guizhen, Wang, Xiyan, Sun, Lin, Gao, Yawen, Niu, Xiaodi, Wang, Hongsu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017250/
https://ncbi.nlm.nih.gov/pubmed/29690584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040977
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