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Discovery and structure–activity relationship analysis of Staphylococcus aureus sortase A inhibitors
Methicillin resistant Staphylococcus aureus (MRSA) is a major health problem that has created a pressing need for new antibiotics. Compounds that inhibit the S. aureus SrtA sortase may function as potent anti-infective agents as this enzyme attaches virulence factors to the cell wall. Using high-thr...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888031/ https://ncbi.nlm.nih.gov/pubmed/19781950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.08.067 |
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