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The Structure of the Staphylococcus aureus Sortase-Substrate Complex Reveals How the Universally Conserved LPXTG Sorting Signal Is Recognized

In Gram-positive bacteria, sortase enzymes assemble surface proteins and pili in the cell wall envelope. Sortases catalyze a transpeptidation reaction that joins a highly conserved LPXTG sorting signal within their polypeptide substrate to the cell wall or to other pilin subunits. The molecular basi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Suree, Nuttee, Liew, Chu Kong, Villareal, Valerie A., Thieu, William, Fadeev, Evgeny A., Clemens, Jeremy J., Jung, Michael E., Clubb, Robert T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782039/
https://ncbi.nlm.nih.gov/pubmed/19592495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022624
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