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Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif

Surface proteins of Staphylococcus aureus are linked to the bacterial cell wall by sortase, an enzyme that cleaves polypeptides at the threonine of the LPXTG motif. Surface proteins can be released from staphylococci by treatment with hydroxylamine, resulting in the formation of threonine hydroxamat...

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Detalhes bibliográficos
Main Authors: Ton-That, Hung, Liu, Gwen, Mazmanian, Sarkis K., Faull, Kym F., Schneewind, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22937/
https://ncbi.nlm.nih.gov/pubmed/10535938
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