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Sortases, Surface Proteins, and Their Roles in Staphylococcus aureus Disease and Vaccine Development

Sortases cleave short peptide motif sequences at the C-terminal end of secreted surface protein precursors and either attach these polypeptides to the peptidoglycan of Gram-positive bacteria or promote their assembly into pilus structures that are also attached to peptidoglycan. Sortase A, the enzym...

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Bibliografiske detaljer
Udgivet i:Microbiol Spectr
Main Authors: Schneewind, Olaf, Missiakas, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: ASM Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386163/
https://ncbi.nlm.nih.gov/pubmed/30737913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/microbiolspec.psib-0004-2018
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