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Sortases, Surface Proteins, and Their Roles in Staphylococcus aureus Disease and Vaccine Development

Sortases cleave short peptide motif sequences at the C-terminal end of secreted surface protein precursors and either attach these polypeptides to the peptidoglycan of Gram-positive bacteria or promote their assembly into pilus structures that are also attached to peptidoglycan. Sortase A, the enzym...

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Detalles Bibliográficos
Publicado en:Microbiol Spectr
Autores principales: Schneewind, Olaf, Missiakas, Dominique
Formato: Artigo
Lenguaje:Inglês
Publicado: ASM Press 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386163/
https://ncbi.nlm.nih.gov/pubmed/30737913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/microbiolspec.psib-0004-2018
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