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Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif

Surface proteins of Staphylococcus aureus are linked to the bacterial cell wall by sortase, an enzyme that cleaves polypeptides at the threonine of the LPXTG motif. Surface proteins can be released from staphylococci by treatment with hydroxylamine, resulting in the formation of threonine hydroxamat...

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Bibliografiska uppgifter
Huvudupphovsmän: Ton-That, Hung, Liu, Gwen, Mazmanian, Sarkis K., Faull, Kym F., Schneewind, Olaf
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC22937/
https://ncbi.nlm.nih.gov/pubmed/10535938
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