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Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus

Surface proteins of Gram-positive bacteria play important roles during the pathogenesis of human infections and require sortase for anchoring to the cell-wall envelope. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of thre...

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Detalhes bibliográficos
Main Authors: Ilangovan, Udayar, Ton-That, Hung, Iwahara, Junji, Schneewind, Olaf, Clubb, Robert T.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC33421/
https://ncbi.nlm.nih.gov/pubmed/11371637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101064198
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