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Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus
Surface proteins of Gram-positive bacteria play important roles during the pathogenesis of human infections and require sortase for anchoring to the cell-wall envelope. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of thre...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33421/ https://ncbi.nlm.nih.gov/pubmed/11371637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.101064198 |
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