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Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif

Surface proteins of Staphylococcus aureus are linked to the bacterial cell wall by sortase, an enzyme that cleaves polypeptides at the threonine of the LPXTG motif. Surface proteins can be released from staphylococci by treatment with hydroxylamine, resulting in the formation of threonine hydroxamat...

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Библиографические подробности
Главные авторы: Ton-That, Hung, Liu, Gwen, Mazmanian, Sarkis K., Faull, Kym F., Schneewind, Olaf
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1999
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC22937/
https://ncbi.nlm.nih.gov/pubmed/10535938
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