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Discovery of a Novel Natural Allosteric Inhibitor That Targets NDM-1 Against Escherichia coli
At present, the resistance of New Delhi metallo-β-lactamase-1 (NDM-1) to carbapenems and cephalosporins, one of the mechanisms of bacterial resistance against β-lactam antibiotics, poses a threat to human health. In this work, based on the virtual ligand screen method, we found that carnosic acid (C...
Shranjeno v:
| izdano v: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7566295/ https://ncbi.nlm.nih.gov/pubmed/33123013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.581001 |
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