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MBRS-30. TORC1/2 INHIBITION SENSITIZES MYC-DRIVEN MEDULLOBLASTOMA CELLS TO CARBOPLATIN CHEMOTHERAPY
Medulloblastoma is the most common malignant pediatric brain tumor. Tumors having high levels of c-MYC have the worst clinical prognosis, with only a minority of patients surviving. We performed an in silico analysis of human stem cell model of medulloblastoma, which predicted mTOR inhibitors as a p...
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| Publié dans: | Neuro Oncol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6012603/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.475 |
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