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MODELLING HIGH MYC MEDULLOBLASTOMA AND OTHER BRAIN TUMORS USING HUMAN NEURAL STEM CELLS
BACKGROUND: We used human fetal neural stem cells dissected from the cerebral cortex, thalamus, cerebellum and brainstem, then propagated as neurospheres, to model a range of brain tumors. Various combinations of oncogenic elements characteristic of medulloblastoma and glioblastoma were introduced i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144476/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.12 |
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