MBRS-30. TORC1/2 INHIBITION SENSITIZES MYC-DRIVEN MEDULLOBLASTOMA CELLS TO CARBOPLATIN CHEMOTHERAPY

Medulloblastoma is the most common malignant pediatric brain tumor. Tumors having high levels of c-MYC have the worst clinical prognosis, with only a minority of patients surviving. We performed an in silico analysis of human stem cell model of medulloblastoma, which predicted mTOR inhibitors as a p...

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Publicado no:Neuro Oncol
Main Authors: Maynard, Rachael, Hanaford, Allison, Poore, Bradley, Rubens, Jeffrey, Archer, Tenley, Tamayo, Pablo, Pomeroy, Scott, Eberhart, Charles, Raabe, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012603/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.475
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