MBRS-30. TORC1/2 INHIBITION SENSITIZES MYC-DRIVEN MEDULLOBLASTOMA CELLS TO CARBOPLATIN CHEMOTHERAPY

Medulloblastoma is the most common malignant pediatric brain tumor. Tumors having high levels of c-MYC have the worst clinical prognosis, with only a minority of patients surviving. We performed an in silico analysis of human stem cell model of medulloblastoma, which predicted mTOR inhibitors as a p...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Maynard, Rachael, Hanaford, Allison, Poore, Bradley, Rubens, Jeffrey, Archer, Tenley, Tamayo, Pablo, Pomeroy, Scott, Eberhart, Charles, Raabe, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Abstracts
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012603/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.475
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky