Glioblastoma-targeted CD4(+) CAR T cells mediate superior antitumor activity

Chimeric antigen receptor–modified (CAR-modified) T cells have shown promising therapeutic effects for hematological malignancies, yet limited and inconsistent efficacy against solid tumors. The refinement of CAR therapy requires an understanding of the optimal characteristics of the cellular produc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Wang, Dongrui, Aguilar, Brenda, Starr, Renate, Alizadeh, Darya, Brito, Alfonso, Sarkissian, Aniee, Ostberg, Julie R., Forman, Stephen J., Brown, Christine E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012522/
https://ncbi.nlm.nih.gov/pubmed/29769444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99048
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