Glioblastoma-targeted CD4(+) CAR T cells mediate superior antitumor activity

Chimeric antigen receptor–modified (CAR-modified) T cells have shown promising therapeutic effects for hematological malignancies, yet limited and inconsistent efficacy against solid tumors. The refinement of CAR therapy requires an understanding of the optimal characteristics of the cellular produc...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Wang, Dongrui, Aguilar, Brenda, Starr, Renate, Alizadeh, Darya, Brito, Alfonso, Sarkissian, Aniee, Ostberg, Julie R., Forman, Stephen J., Brown, Christine E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012522/
https://ncbi.nlm.nih.gov/pubmed/29769444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99048
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