ATIM-17. PEMBROLIZUMAB BLOCKS PD-1 ON CAR T CELLS ADMINISTERED INTRAVENTRICULARLY TO GLIOBLASTOMA PATIENTS

BACKGROUND: Checkpoint inhibitors have shown efficacy in other solid tumors and are being studied in glioblastoma. For patients treated with anti-PD-1 monoclonal antibodies, such as pembrolizumab, CSF concentrations and blockade of PD-1 on T cells present in the CSF have not been reported. Such info...

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Publicado no:Neuro Oncol
Main Authors: Portnow, Jana, Synold, Timothy, Tran, Vivi, Chiu, Vivian, Alizadeh, Darya, Wang, Dongrui, Brito, Alfonso, Kilpatrick, Julie, Mcnamara, Paige, Forman, Stephen, Badie, Behnam, Brown, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216123/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.012
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