Glioblastoma-targeted CD4(+) CAR T cells mediate superior antitumor activity

Chimeric antigen receptor–modified (CAR-modified) T cells have shown promising therapeutic effects for hematological malignancies, yet limited and inconsistent efficacy against solid tumors. The refinement of CAR therapy requires an understanding of the optimal characteristics of the cellular produc...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Wang, Dongrui, Aguilar, Brenda, Starr, Renate, Alizadeh, Darya, Brito, Alfonso, Sarkissian, Aniee, Ostberg, Julie R., Forman, Stephen J., Brown, Christine E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012522/
https://ncbi.nlm.nih.gov/pubmed/29769444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99048
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