LGG-11. REGULATION OF ONCOGENE-INDUCED SENESCENCE IN PILOCYTIC ASTROCYTOMA

The main challenge in the clinical management of pilocytic astrocytoma (PA) is its unpredictable growth behavior. PA cells are driven into oncogene-induced senescence (OIS) by aberrant MAPK activation. In other senescence models OIS was shown to be regulated and maintained by the senescence-associat...

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Publié dans:Neuro Oncol
Auteurs principaux: Buhl, Juliane L, Selt, Florian, Hielscher, Thomas, Sahm, Felix, Capper, David, Schramm, Kathrin, Ridinger, Johannes, Usta, Diren, Ecker, Jonas, Oehme, Ina, van Tilburg, Cornelis M, Kool, Marcel, von Deimling, Andreas, Schuhmann, Martin U, Korshunov, Andrey, Pfister, Stefan M, Brummer, Tilman, Jones, David T W, Witt, Olaf, Milde, Till
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012159/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.353
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