LGG-11. REGULATION OF ONCOGENE-INDUCED SENESCENCE IN PILOCYTIC ASTROCYTOMA

The main challenge in the clinical management of pilocytic astrocytoma (PA) is its unpredictable growth behavior. PA cells are driven into oncogene-induced senescence (OIS) by aberrant MAPK activation. In other senescence models OIS was shown to be regulated and maintained by the senescence-associat...

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Vydáno v:Neuro Oncol
Hlavní autoři: Buhl, Juliane L, Selt, Florian, Hielscher, Thomas, Sahm, Felix, Capper, David, Schramm, Kathrin, Ridinger, Johannes, Usta, Diren, Ecker, Jonas, Oehme, Ina, van Tilburg, Cornelis M, Kool, Marcel, von Deimling, Andreas, Schuhmann, Martin U, Korshunov, Andrey, Pfister, Stefan M, Brummer, Tilman, Jones, David T W, Witt, Olaf, Milde, Till
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012159/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.353
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