LGG-11. REGULATION OF ONCOGENE-INDUCED SENESCENCE IN PILOCYTIC ASTROCYTOMA

The main challenge in the clinical management of pilocytic astrocytoma (PA) is its unpredictable growth behavior. PA cells are driven into oncogene-induced senescence (OIS) by aberrant MAPK activation. In other senescence models OIS was shown to be regulated and maintained by the senescence-associat...

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Publicado no:Neuro Oncol
Main Authors: Buhl, Juliane L, Selt, Florian, Hielscher, Thomas, Sahm, Felix, Capper, David, Schramm, Kathrin, Ridinger, Johannes, Usta, Diren, Ecker, Jonas, Oehme, Ina, van Tilburg, Cornelis M, Kool, Marcel, von Deimling, Andreas, Schuhmann, Martin U, Korshunov, Andrey, Pfister, Stefan M, Brummer, Tilman, Jones, David T W, Witt, Olaf, Milde, Till
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012159/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.353
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