LGG-11. REGULATION OF ONCOGENE-INDUCED SENESCENCE IN PILOCYTIC ASTROCYTOMA

The main challenge in the clinical management of pilocytic astrocytoma (PA) is its unpredictable growth behavior. PA cells are driven into oncogene-induced senescence (OIS) by aberrant MAPK activation. In other senescence models OIS was shown to be regulated and maintained by the senescence-associat...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Buhl, Juliane L, Selt, Florian, Hielscher, Thomas, Sahm, Felix, Capper, David, Schramm, Kathrin, Ridinger, Johannes, Usta, Diren, Ecker, Jonas, Oehme, Ina, van Tilburg, Cornelis M, Kool, Marcel, von Deimling, Andreas, Schuhmann, Martin U, Korshunov, Andrey, Pfister, Stefan M, Brummer, Tilman, Jones, David T W, Witt, Olaf, Milde, Till
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012159/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.353
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