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Mechanisms of acetaminophen-induced liver injury and its implications for therapeutic interventions
Acetaminophen (APAP) overdose is the leading cause of drug-induced acute liver failure in many developed countries. Mitochondrial oxidative stress is considered to be the predominant cellular event in APAP-induced liver injury. Accordingly, N-acetyl cysteine, a known scavenger of reactive oxygen spe...
Guardat en:
| Publicat a: | Redox Biol |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6006912/ https://ncbi.nlm.nih.gov/pubmed/29753208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.04.019 |
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