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Protective role of p53 in acetaminophen hepatotoxicity

p53 is a tumor suppressor with a pro-death role in many conditions. However, in some contexts, evidence supports a pro-survival function. p53 has been shown to be activated in acetaminophen (APAP) toxicity but the impact of this on toxicity is uncertain. In the present study, we have found that p53...

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Bibliografiske detaljer
Udgivet i:Free Radic Biol Med
Main Authors: Huo, Yazhen, Yin, Shutao, Yan, Mingzhu, Win, Sanda, Than, Tin Aung, Aghajan, Mariam, Hu, Hongbo, Kaplowitz, Neil
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396540/
https://ncbi.nlm.nih.gov/pubmed/28196650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.02.028
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