Protective role of p53 in acetaminophen hepatotoxicity

p53 is a tumor suppressor with a pro-death role in many conditions. However, in some contexts, evidence supports a pro-survival function. p53 has been shown to be activated in acetaminophen (APAP) toxicity but the impact of this on toxicity is uncertain. In the present study, we have found that p53...

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Detaylı Bibliyografya
Yayımlandı:Free Radic Biol Med
Asıl Yazarlar: Huo, Yazhen, Yin, Shutao, Yan, Mingzhu, Win, Sanda, Than, Tin Aung, Aghajan, Mariam, Hu, Hongbo, Kaplowitz, Neil
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396540/
https://ncbi.nlm.nih.gov/pubmed/28196650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.02.028
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