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Protective role of p53 in acetaminophen hepatotoxicity

p53 is a tumor suppressor with a pro-death role in many conditions. However, in some contexts, evidence supports a pro-survival function. p53 has been shown to be activated in acetaminophen (APAP) toxicity but the impact of this on toxicity is uncertain. In the present study, we have found that p53...

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書目詳細資料
發表在:Free Radic Biol Med
Main Authors: Huo, Yazhen, Yin, Shutao, Yan, Mingzhu, Win, Sanda, Than, Tin Aung, Aghajan, Mariam, Hu, Hongbo, Kaplowitz, Neil
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396540/
https://ncbi.nlm.nih.gov/pubmed/28196650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.02.028
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