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Glycycoumarin protects mice against acetaminophen‐induced liver injury predominantly via activating sustained autophagy

BACKGROUND AND PURPOSE: Acetaminophen‐induced acute liver injury (AILI) is the most frequent cause of acute liver failure in developed countries. Given the significant limitations associated with N‐acetyl cysteine, the only antidote used to treat AILI, the development of novel therapeutic approaches...

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Bibliografische gegevens
Gepubliceerd in:Br J Pharmacol
Hoofdauteurs: Yan, Mingzhu, Ye, Linhu, Yin, Shutao, Lu, Xiaotong, Liu, Xiaoyi, Lu, Shangyun, Cui, Jinling, Fan, Lihong, Kaplowitz, Neil, Hu, Hongbo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135785/
https://ncbi.nlm.nih.gov/pubmed/30024038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14444
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