Glycycoumarin protects mice against acetaminophen‐induced liver injury predominantly via activating sustained autophagy

BACKGROUND AND PURPOSE: Acetaminophen‐induced acute liver injury (AILI) is the most frequent cause of acute liver failure in developed countries. Given the significant limitations associated with N‐acetyl cysteine, the only antidote used to treat AILI, the development of novel therapeutic approaches...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Yan, Mingzhu, Ye, Linhu, Yin, Shutao, Lu, Xiaotong, Liu, Xiaoyi, Lu, Shangyun, Cui, Jinling, Fan, Lihong, Kaplowitz, Neil, Hu, Hongbo
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135785/
https://ncbi.nlm.nih.gov/pubmed/30024038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14444
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