Glycycoumarin protects mice against acetaminophen‐induced liver injury predominantly via activating sustained autophagy

BACKGROUND AND PURPOSE: Acetaminophen‐induced acute liver injury (AILI) is the most frequent cause of acute liver failure in developed countries. Given the significant limitations associated with N‐acetyl cysteine, the only antidote used to treat AILI, the development of novel therapeutic approaches...

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Publicat a:Br J Pharmacol
Autors principals: Yan, Mingzhu, Ye, Linhu, Yin, Shutao, Lu, Xiaotong, Liu, Xiaoyi, Lu, Shangyun, Cui, Jinling, Fan, Lihong, Kaplowitz, Neil, Hu, Hongbo
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135785/
https://ncbi.nlm.nih.gov/pubmed/30024038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14444
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